![]() Results indicate that there is familial aggregation of paratuberculosis ELISA results in beef cattle and suggest that genetic selection based on paratuberculosis ELISA status may decrease seroprevalence. A significant positive linear association was also observed between dam and offspring log-transformed S:P ratios. The odds of being classified as "suspect" or greater based on ELISA results were 4.6 times greater for offspring of dams with similarly increased S:P ratios. Significant associations were identified between some ancestors and offspring ELISA status. The association between ELISA status of the dam and her offspring was assessed using linear mixed-effect models. Associations between ancestors and paratuberculosis ELISA status of offspring were assessed using conditional logistic regression. Diagnostic test results were indicative of substantial numbers of false-positive serological reactions consistent with environmental exposure to non-MAP Mycobacterium spp. Texas Longhorn cattle (n=715) greater than 2years of age were sampled for paratuberculosis testing using ELISA and fecal culture. The objective of this cross-sectional study was to estimate familial associations with paratuberculosis ELISA status in beef cattle. Osterstock, Jason B Fosgate, Geoffrey T Cohen, Noah D Derr, James N Manning, Elizabeth J B Collins, Michael T Roussel, Allen J Familial associations with paratuberculosis ELISA results in Texas Longhorn cattle.
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